There are so many issues that your question raises ... as the reply posts above mine prove. I'm an old office worker with no woodwork training at all, and the only musical instrument I can play is a CD player. Yet for some strange reason I looked at one of my sons' Fenders and figured "that couldn't be too difficult to make?!" So we gave it a go. I was confident we could make something that would 'work' ... but the question would be how well it would 'work'. At worst I figured we'd end up with a fairly impressive wall hanging. When we plugged the end result in and it played [not at first, but that's another story ... about his amp!] we were one rapt father and son team. It tunes correctly, it plays, it's our design, and it looks great. When friends and relatives look at it with awe you can imagine what a real buzz it is. I learnt truck-loads from the process and from lurking around the talented people (guys?) on this forum ... and I learnt how little I actually knew before I started. Our guitar is not perfect, and there are so many things we will know and do better when we start build number 2 ... but only a player or a forum member would spot the mistakes and short-cuts. So the short answer is, if I can do it with my limited skills and music knowledge, then you certainly should be able to. But plan out and draw up what you're going to build ... run your ideas past the very giving (and honest!) people on this forum, be prepared to take crticism and to listen and learn ... and finally, you will find the answer to just about any question you might have in these forums, so practice with the search function. And if that fails ... just ask.
Sorry for the longish post ... but I feel like I could now write a thesis on "The Transition from Conscious Incompetence to Unconscious Competence of the Newbie Member and Builder on the Project Guitar Forum".
Enjoy the ride!!