Hello and welcome,
I have a Floyd Rose II with a D-TUNA, my experience:
Ok I have NEVER used it in almost 2 years, why, I use the bar a LOT! with the D-TUNA the guitar tends to detune unless you block the trem...and I dont want to block it ya know...flubbers, pulls, dives...etc..(all that fun stuff! ), so yes you will have to block your trem if you decide to purshase it...if you are like me and dont want to block it... dont use it, unless you want to have tuning problems...I dont really play 6th down to D or C, I wanted just to try...the D-TUNE would be real good for a non-trem guitar, my 2 cents man, hope this helped.
Ivan