I know Ibanez has a couple basses made out of some synthetic materials, and Gibson has a "Smartwood" series which is also some form of something that's not actually wooden.
Don't do it, you'll end up probably not doing anything with the project.
I tried something similar, and the body just looked ugly and really small afterwards.
Deathmetal bass?
You should string it up BEAD so you can fill that low range up even more.
Or if you're REALLY daring, string it up like some Warwick I saw that was strung F#BEA