I used to have a perspex Aria Legend solid electric guitar, based loosely on the stylings of the now legendary Fender Jazzmaster guitar. It had two powerful humbucking pickups, 1 volume, 1 tone and 3-way pickup selector, a 22-fret neck with rosewood fingerboard, and body and headstock made from clear perspex making it look ultra cool. The perspex headstock was scarfed onto a wooden neck (which looked like maple) and the joint was absolutely seamless.
I certainly had no complaints about the tone. Indeed, the perspex body gave the guitar quite incredible sustain, although I did wonder about how the "swimming pool" pickup cavity - surely, the sustain would have been better individual cavities had been routed for each pickup? Only problem here would be that it'd have been even heavier. The beast weighed a ton as it was!