It looks like you're going about it systematically. I recall in your other thread (a year ago maybe) that people brought up how the nodes shift for every fretted note. It looks like you're taking this into consideration, which makes your theory far more valid in my mind.
Other things to consider... harmonics of open string even when it's fretted, string ringing along its ENTIRE length (behind nut and bridge), equal tempered frets being out of tune with open string harmonic nodes, etc., etc., etc.
I say, dive into the dirty details!
I would have to disagree with the other replies--I DO think there's something to this, and I don't think it comes down to "the 2nd octave is a sweet spot and it's all subjective".