make a strat shaped guitar with a maple neck, alder body, synchronised tremolo, 3 single coil pickups with the bridge pickup angled towards the neck and you might get the sound.... lol
basically - all of the above contribute to the sound character of a Strat, it depends on how close you want to be to a Strat sound, but changing the body shape shouldn't affect it too much as long as the size/weight/density are about the same