I have to say that i am split with this
GE Jones has a point that nowadays, due to digital electronics, the actually guitar you play matters alot less. for example. my school invested in one of the nice shiny red Line 6 pods for the school studios. a friend of mine was showing it to me and after a quick tinker he dials stuff into the processor. he set it upto replicate a Tube screamer running through a marshal stack. well bugger me it sounded pretty fecking awesome. he went through a load of stuff on there. its got presets for black sabbath (paranoid is what i heard, again it was spot on the right sound), van halen and a host of others. he was playing all this through his kramer striker. Basswood body i will add.
Digital electronics can do all of this and without too much trouble.
however, i personally dislike digital effects. iwould much rather have a real tube screamer and a real marshal stack and be able to plug in a real guitar that i know is goingto sound nice without me having to spend an hour programing everything into a pod.
as with everything, personal preference reigns lol