#1 Thank yourself for asking questions before attepting to do the work, that just put you ahead of most.
The screws holding a neck on are there just so you CAN take the neck on and off. That being said, you can also do damage and make it loose if you are careless. Might want to stay away from the power driver too.
Repainting? or will you be taking off the finish and starting with bare wood? You would first need to know what finish is on there now. If you let us know if is an actual Fender, a Squire, or a copy, and maybe even how old it is, one of the paint experts can tell you what is on there now and what would be best to use. We will also be able to give advice about if you should or shouldn't refinish it.
There is no certain lacquer that will give you factory results, or maybe a better way of putting it is that they all will give you factory results, but the key is your sanding skills, what you shoot the lacquer with and the time you spend buffing. There are many tutorials that will help you get a better understanding, look for them here in the forum ad off the main site too.