PRS and telecaster guitars have different scale lengths, neck pocket types, neck angles, etc., so you will have to put in a lot of leg work to mix two different styles of guitars like this relative to doing a straight up clone. Don't assume that any holes will line up or anything like that, you will have to do all that from scratch, preferably with parts in-hand. If I were doing a first build again, I would do a clone or very subtle variation of a well-known guitar instead of the full blown, designed from the ground up build that I did. I made a lot of mistakes and ended up scrapping the guitar (it played, but was not particularly well done). You may be different than I and are welcome to try, but my suggestion based on your questions (I'm not putting you down, just saying that based on your questions there are lots of things you need to read up on, we all have to) it might have a pretty good chance of not turning out quite as well as you would like. Then again, you might be the type who studies and researches everything to death before practicing which you do before actually building. I'm much more of a fly-by-the-seat-of-my-pants type guy who likes see what happens.