I think thats a closed option for me, cause the truss rod is there and fretboard is glued.
Only thing I have to decide is where I am gonna dig hole for neckpickup.
I don't know about that optimum spot thing, cause pickup is gonna be "out of place" anyway, compared to factory made guitars with 22 frets. The fretboard I am using is for 24 frets and guitar I´m building is a neckthru SG.