I think that, to a certain degree, it's a matter of deciding whether your goal is to be in business to make money or to pursue your creative muse. The two are not neccessarily mutually exclusive, but it seems to be fairly rare for both to co-exist. Particularly for those who are less established in the marketplace.
And really, if your goal is to build a guitar that you find interesting, and the design and building process is a creative release for you, then what difference does it make if anyone else wants to pay big money for it? Pick yourself up and be happy with the unique works of art that you are creating.
Or...Go out and do what it takes to make money, without regards to your creative whims. Maybe one day you'll get to the point where you can indulge yourself and people will be falling over themselves to outbid each other for it.
So, which is it going to be?